68 Results for "

Acanthopanax senticosus (Rupr. et Maxim.) Harms

" in MedChemExpress (MCE) Product Catalog:
Products (68)

68 Results for "Acanthopanax senticosus (Rupr. et Maxim.) Harms" in MCE Product Catalog:

7
Peiminine
Peiminine
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7 Publications Verification
Cat. No.: HY-N0213
CAS No.: 18059-10-4
Synonyms: Verticinone; Raddeanine
Category:  

Alkaloids Piperidine Alkaloids Liliaceae Fritillaria thunbergii Miq. Plants Disease Research Fields Cancer

Target:  

Autophagy Caspase Bcl-2 Family PARP p38 MAPK ERK NF-κB Apoptosis

Peiminine is a compound that can be isolated from Bolbostemma paniculatum (Maxim) Franquet (Cucurbitaceae family). Peiminine can induce apoptosis in human hepatocellular carcinoma HepG2 cells through both extrinsic and intrinsic apoptotic pathways. Peiminine has anti-inflammatory, anticancer, anti-osteoporosis, cardioprotective and other activities in many animal models .
5
iMDK
iMDK
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5 Cited Publications
Cat. No.: HY-110171
CAS No.: 881970-80-5
Purity:  99.35%
Target:  

PI3K

Research Areas:  

Cancer

iMDK is a potent PI3K inhibitor and inhibits the growth factor MDK (also known as midkine or MK). iMDK suppresses non-small cell lung cancer (NSCLC) cooperatively with A MEK inhibitor without harming normal cells and mice .
5
iMDK quarterhydrate
iMDK quarterhydrate
0 Images
5 Cited Publications
Cat. No.: HY-110171A
Purity:  99.37%
Target:  

PI3K

Research Areas:  

Cancer

iMDK quarterhydrate is a potent PI3K inhibitor and inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate suppresses non-small cell lung cancer (NSCLC) cooperatively with A MEK inhibitor without harming normal cells and mice .
4
Isofraxidin
Isofraxidin
0 Images
4 Cited Publications
Cat. No.: HY-N0774
CAS No.: 486-21-5
Category:  

Monophenols Coumarins Phenols Acanthopanax senticosus (Rupr. et Maxim.) Harms Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology Araliaceae

Target:  

ERK COX MMP Toll-like Receptor (TLR)

Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells . Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation .
3
Noricaritin
Noricaritin
0 Images
3 Cited Publications
Cat. No.: HY-N1413
CAS No.: 5240-95-9
Category:  

Flavonols Flavonoids Phenols Polyphenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields Cancer

Target:  

Others

Noricaritin is a flavonoid sourced from roots of Epimedium brevicornu Maxim.
2
Brassinin
Brassinin
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2 Cited Publications
Cat. No.: HY-111334
CAS No.: 105748-59-2
Purity:  99.74%
Synonyms: Brassinine
Category:  

Beassica pekinensis (Lour. ) Rupr. Alkaloids Cruciferae Cosmetic Research Plants Disease Research Fields Cancer Indole Alkaloids

Target:  

Endogenous Metabolite

Brassinin is the metabolism of a phytoalexin from Beassica pekinensis (Lour. ) Rupr. .
1
Leucomalachite green
Leucomalachite green
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1 Cited Publications
Cat. No.: HY-D0300
CAS No.: 129-73-7
Leucomalachite green is the major reduced metabolite of malachite green (MG) and has lower cytotoxicity (such as HEp-2 and Caco-2) than malachite green. Leucomalachite green may be involved in interfering with cell metabolism or redox balance and can be used to evaluate its potential harm to human cells as a food contaminant .
Tetradecanoylcarnitine
Tetradecanoylcarnitine
0 Images
Cat. No.: HY-113201
CAS No.: 25597-07-3
Purity:  ≥98.0%
Category:  

Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Tetradecanoylcarnitine is an acylcarnitine involved in mitochondrial β-oxidation of long-chain saturated fatty acids and fatty acid metabolism. Tetradecanoylcarnitine serves as a biomarker for very long-chain acyl-CoA dehydrogenase deficiency and MPTP (HY-15608)-induced Parkinson's disease. Tetradecanoylcarnitine exhibits a characteristic significant elevation in plasma levels in patients with sarcopenia, including those complicated with hypertension, and this elevation is closely associated with an increased risk of death. Tetradecanoylcarnitine is widely used in research on the pathological mechanisms of diseases such as Parkinson's disease and sarcopenia .
Isocorydine
Isocorydine
0 Images
Cat. No.: HY-N2591
CAS No.: 475-67-2
Category:  

Alkaloids other families Monophenols Phenols Plants Disease Research Fields Isoquinoline Alkaloids Cancer

Target:  

Endogenous Metabolite

Isocorydine is isolated from Dicranostigma leptopodum (Maxim.) Fedde (DLF). Isocorydine combines with Doxorubicin (DOX) has a promising potential to eradicate hepatocellular carcinoma (HCC) .
Methylchloroisothiazolinone
Methylchloroisothiazolinone
0 Images
Cat. No.: HY-W041608
CAS No.: 26172-55-4
Target:  

NF-κB Toll-like Receptor (TLR) Bacterial

Research Areas:  

Infection Inflammation/Immunology

Methylchloroisothiazolinone is a widely used fungicide and also an aquatic pollutant with pro-inflammatory activity and neurotoxicity. Methylchloroisothiazolinone induces the production of pro-inflammatory cytokines (such as IL-1β, TNF-α, IL-6) by activating the NF-κB signaling pathway and upregulating TLR4 expression, thereby triggering allergic contact dermatitis. Methylchloroisothiazolinone reduces cholinesterase activity and exacerbates oxidative stress by impairing catalase activity and disrupting redox balance. Methylchloroisothiazolinone poses significant harm to Mediterranean mussels, reducing the viability of hemocytes and digestive gland cells, inhibiting immune phagocytic function, and disrupting osmoregulatory capacity. Methylchloroisothiazolinone is used in studies on allergic contact dermatitis and related immunotoxicity mechanisms .
Ciwujianoside C3
Ciwujianoside C3
0 Images
Cat. No.: HY-N4134
CAS No.: 114906-74-0
Category:  

Acanthopanax henryi (Oliv.) Harms Terpenoids Plants Disease Research Fields Inflammation/Immunology Pentacyclic Triterpenoids Araliaceae

Target:  

NO Synthase

Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory .
Acanthopanaxoside B
Acanthopanaxoside B
0 Images
Cat. No.: HY-N4135
CAS No.: 915792-03-9
Category:  

Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Terpenoids Metabolic Disease Plants Disease Research Fields Araliaceae

Target:  

Others

Acanthopanaxoside B is a triterpenoid saponin isolated from the leaves of Acanthopanax senticosus .
(-)-Sesamin
(-)-Sesamin
0 Images
Cat. No.: HY-N0121A
CAS No.: 13079-95-3
Category:  

Asarum forbesii Maxim. Other Diseases Lignans Phenylpropanoids Plants Disease Research Fields Aristolochiaceae

Target:  

Others

(-)-Sesamin isolated from Asarum forbesii Maxim, is an isomer of Sesamin. Sesamin is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis .
13β-Hydroxylupanine
13β-Hydroxylupanine
0 Images
Cat. No.: HY-N10983
CAS No.: 6870-60-6
Category:  

Alkaloids Piperidine Alkaloids Caulophyllum robustum Maxim. Plants Berberidaceae

Target:  

Others

13β-Hydroxylupanine is a natural product that can be found in Caulophyllum robustum Maxim .
Caulophine
Caulophine
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Cat. No.: HY-N8598
CAS No.: 1159989-19-1
Category:  

Alkaloids Caulophyllum robustum Maxim. Plants Berberidaceae

Target:  

Others

Caulophine is a fluoroketone alkaloid isolated from Caulophyllum robustum MAXIM. Caulophine has antioxidant activity and the ability to protect cardiomyocytes from oxidative and ischemic damage, providing potential value for coronary heart disease research .
Ciwujianoside E
Ciwujianoside E
0 Images
Cat. No.: HY-N8763
CAS No.: 114912-36-6
Synonyms: Guaianin A
Category:  

Tetracyclic Triterpenoids Terpenoids Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Araliaceae

Target:  

Others

Ciwujianoside E is a triterpene saponin that can be isolated from Acanthopanax senticosus. Ciwujianoside E can be used in study sedative-hypnotic drug .
Isofraxidin (Standard)
Isofraxidin (Standard)
0 Images
Cat. No.: HY-N0774R
CAS No.: 486-21-5
Category:  

Monophenols Coumarins Phenols Acanthopanax senticosus (Rupr. et Maxim.) Harms Phenylpropanoids Plants Araliaceae

Target:  

ERK Reference Standards COX MMP Toll-like Receptor (TLR)

Isofraxidin (Standard) is the analytical standard of Isofraxidin. This product is intended for research and analytical applications. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells . Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation .
Caulophylline B
Caulophylline B
0 Images
Cat. No.: HY-N6672
CAS No.: 1359978-55-4
Category:  

Alkaloids Caulophyllum robustum Maxim. Phenols Polyphenols Plants Berberidaceae Disease Research Fields Inflammation/Immunology

Target:  

Others

Caulophylline B is a fluorenone alkaloid isolated from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical .
Purpurogallin carboxylic acid
Purpurogallin carboxylic acid
0 Images
Cat. No.: HY-N6877
CAS No.: 5146-12-3
Category:  

Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae

Target:  

Others

Purpurogallin carboxylic acid, isolated from Macleaya microcarpa (Maxim.) Fedde, is an oxidation product of gallic acid in fermented tea. Purpurogallin carboxylic acid has anti-cancer activity .
Przewalskinic acid A
Przewalskinic acid A
0 Images
Cat. No.: HY-N5057
CAS No.: 136112-75-9
Category:  

Cardiovascular Disease Labiatae Terpenoids Samanea saman (Jacq.) Merr. Phenols Polyphenols Diterpenoids Plants Disease Research Fields

Target:  

Others

Przewalskinic acid A is a phenolic acid found in the Salvia przewalskii Maxim herb. Phenolic acids show potent antioxidant activities and potential effects in protecting against brain and heart damage caused by ischemia reperfusion .
Assay Types